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Evidence

Evidence & Independent Review

Published performance stated exactly as studied, cited inline — alongside what independent reviewers said about it, and the limitations they raised.

How we label evidence

Every protocol carries one of these labels. They are not interchangeable: a described technique is not a comparison study, and neither is a case series. The label states the strongest claim that protocol’s own citations support.

Published method
Technique described, not clinical-outcome validation
Prospective comparison
Agreement/performance study
Retrospective implementation
Feasibility in clinical use
Case series
Descriptive evidence without comparator
Educational framework
Derived application, not directly validated
Investigational
Research use only
In development
Not ready for clinical teaching

Published studies and case series

Original research on EASy — the papers that collected patient data. The methods and protocol papers, reviews, and book chapters are on publications.

  • Retrospective exploratory case series — EASy-PDA

    Bughrara N, Tso MS, Weigand ME, et al. Integrating Rapid Cardiopulmonary and Gastric Ultrasound for Emergency Airway Management in Critically Ill Patients: A Case Series of Resident-Performed Echocardiographic Assessment Using Subcostal-Only-View in Physiologically Difficult Airway. Crit Care Explor 2025;7(11):e1340.

    30 patients needing emergency airway management outside the operating room, scanned by trained anesthesiology residents before induction. Mean examination time 2.40 minutes; findings were sufficient to inform management in 26 of 30 (86.7%), prompting an emergent pericardial window in one patient and gastric decompression in two. The subcostal four-chamber view could not be obtained in one patient because of severe abdominal pain. A feasibility study: it was not designed to show whether EASy-PDA reduces peri-intubation complications or improves outcomes, and does not establish that it does.

    doi:10.1097/CCE.0000000000001340
  • Implementation study

    Bughrara N, Neilson MR, Jones S, Workman L, Chopra A, Pustavoitau A. Is 1 day of focused training in echocardiographic assessment using subxiphoid-only (EASy) examination enough? A tertiary hospital response to COVID-19. Crit Care Explor 2024;6(3):e1038.

    doi:10.1097/CCE.0000000000001038
  • Prospective observational study

    Bughrara N, Renew JR, Alabre K, et al. Comparison of qualitative information obtained with the echocardiographic assessment using subcostal-only view and focused transthoracic echocardiography examinations. Can J Anaesth 2022;69(2):196–204.

    doi:10.1007/s12630-021-02152-6
  • Case series

    Bughrara N, Herrick SL, Leimer E, Sirigaddi K, Roberts K, Pustavoitau A. Focused cardiac ultrasound and the periresuscitative period: a case series of resident-performed echocardiographic assessment using subcostal-only view in advanced life support. A A Pract 2020;14(10):e01278.

    doi:10.1213/XAA.0000000000001278

Independent Commentary

Two independent groups assessed the published EASy work in Can J Anaesth. These are their voices, not ours.

The editorialists commend the work for refining “the minimum competency standards of the operator” and the scope of point-of-care ultrasound that still yields clinically valuable information — while reducing the time the scan takes.
— Fiorini & Basmaji, editorial, Can J Anaesth 2022;69(2):187–191doi:10.1007/s12630-021-02151-7
An independent group from Catania, London, and Cambridge judged the study capable of laying the foundations for a shift in basic critical care echocardiography training, and suggested “EASY will become the first approach novices learn.”
— Sanfilippo, La Via, Flower, Madhivathanan & Astuto, correspondence, Can J Anaesth 2022doi:10.1007/s12630-022-02225-0

Performance

Fast enough to repeat

Prospective comparison — mean examination time, novice sonographers

4 minEASy
16 minFocused transthoracic echo

Protocols that take less time are more likely to be repeated when the patient changes.

Published novice performance averaged approximately 4–4.3 minutes. Through deliberate practice and supervised repetition, the EASy competency pathway targets reliable completion in under 3 minutes while obtaining adequate-quality images.

Fiorini & Basmaji, Can J Anaesth 2022;69(2):187–191

Compared against focused transthoracic echocardiography using parasternal, apical, and subcostal windows, subcostal-only assessment showed almost perfect agreement for pericardial effusion (Gwet's AC1 0.98), interventricular septal motion (0.92), and RV contractility (0.84), and substantial agreement for RV size (0.70), LV size (0.73), and LV contractility (0.73). (Can J Anaesth 2022)

Limitations

The window fails in a meaningful minority. Of the 102 patients in the comparison study, 82 yielded good or adequate subcostal images and were analyzed; in the other 20 the images were poor quality or could not be obtained. The editorialists note that setting those aside may overestimate the benefit of the assessment, and conclude that this view cannot be relied on alone for a significant number of patients.

The conclusion is conditional. When subcostal images could be obtained, the qualitative information was sufficiently accurate compared with full focused transthoracic echocardiography.

Interpretation in that study was performed by experts, who may require fewer data points than novices to act — which is why the EASy pathway keeps interpretation supervised.

Agreement was measured in aggregate. Gwet's coefficient does not show whether disagreements clustered on ruling pathology in or ruling it out.

EASy is not an accreditation pathway. Independent commentary states that in isolation it is unlikely to be sufficient for accreditation in critical care echocardiography.

Future validation

Both commentaries call for external validation, and one recommends full adherence to the PRICES reporting standard for critical care echocardiography research. Prospective multicentre evaluation is the next step, and EASy's development follows that roadmap.

Looking for the full bibliography? View all publications.